Inferring protein interactions from phylogenetic distance matrices
نویسندگان
چکیده
منابع مشابه
Inferring protein interactions from phylogenetic distance matrices
Finding the interacting pairs of proteins between two different protein families whose members are known to interact is an important problem in molecular biology. We developed and tested an algorithm that finds optimal matches between two families of proteins by comparing their distance matrices. A distance matrix provides a measure of the sequence similarity of proteins within a family. Since ...
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To elucidate protein interaction networks is one of the major goals of functional genomics for whole organisms. So far, various computational methods have been proposed for inference of protein-protein interactions. Based on the association method by Sprinzak et al., we propose an association probabilistic method in this short communication to infer protein interactions directly from the experi...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2003
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btg278